Sildenafil Citrate, the active ingredient in Malegra 200, is a PDE5 inhibitor. It works by blocking the enzyme PDE5, which breaks down cyclic GMP—a compound that helps relax smooth muscles and dilate blood vessels in the penis. By inhibiting PDE5, Sildenafil increases the levels of cyclic GMP, allowing more blood to flow into the penis during sexual arousal, which helps to achieve and maintain an erection.

Malegra 200 is primarily prescribed to men with erectile dysfunction (ED), helping them achieve and maintain an erection during sexual activity. It is especially useful in cases where lower doses of Sildenafil have not been effective. Sildenafil is sometimes used in the treatment of pulmonary arterial hypertension, though this indication requires a different dosage.

Malegra 200 is a potent medication used to treat erectile dysfunction in men, particularly for those who do not respond to lower doses of Sildenafil (e.g., 50 mg or 100 mg). It works by increasing blood flow to the penis, helping men achieve and maintain an erection during sexual activity. However, because of its high dosage, it should only be taken under medical supervision, particularly if lower doses have not been effective.